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In the field of assisted reproduction, scientific rigour and clinical experience go hand in hand to achieve results that have a direct impact on treatment outcomes. One of these advances has recently been made by the Ovolearning team, whose study has been published in one of the most influential journals in the sector: Journal of Assisted Reproduction and Genetics, recognised and soon to be indexed in Pubmed in the biomedical database PubMed.
A protocol applicable regardless of the medium
The main objective of the study was to test the efficacy of the Universal Warming Protocol (UWP) when used with different devitrification medium, all applied on eggs previously vitrified in a single bank, Ovobank (Spain). The hypothesis was clear: to demonstrate that the medium used for devitrification does not negatively affect the result, even if it does not coincide with the one used for vitrification.
Ovolearning scientific study design: precision and control
The work was carried out in a multicentre manner and analysed a total of 2,172 metaphase II eggs. These were devitrified in three different centres using three internationally recognised commercial medium:
- Kitazato (Japan)
- Irvine Scientific (USA)
- RapidWarm (Sweden)
The parameters analysed included survival rates, fertilisation, cleavage, development to blastocyst, biochemical pregnancy (after transfer at D+3 and D+5) and clinical pregnancy.
Results: the brand does not make a difference
The findings were clear: the rates obtained showed no statistically significant differences between the different media used for devitrification. This means that the medium used for this step does not determine the success of the procedure, which is a key advantage for breeding centres around the world.
Practical and clinical impact of the Ovolearning scientific study
This study provides a great opportunity to standardise processes, make the choice of media more flexible depending on availability or cost, and facilitate international collaboration between centres. Thanks to this evidence, it is possible to devitrify eggs with different kits without compromising quality or clinical outcomes.
It also greatly facilitates the exchange of vitrified eggs between countries or clinics with different protocols, reducing technical and commercial barriers.
A further step towards a universal embryology
This achievement consolidates Ovolearning as a reference not only in embryological training, but also in applied research. The publication in PubMed is not only a recognition of the study, but also of an entire team committed to scientific excellence, the improvement of protocols and the promotion of global reproductive medicine.
In short, it is research that contributes directly to the quality of care, offering practical solutions with scientific evidence. Because behind every successfully devitrified oocyte, there is a story of effort, precision and science well done.
