Genetic Matching, as the title of this blog suggests, is essential when selecting egg donors and sperm donors. However, before delving deeper into the subject, let’s clarify what this concept entails.
By Matching, or “making a match,” we typically refer to finding the right person for a romantic relationship. When we apply this concept to the genetic field, it can be defined as the compatibility search between the genetic profile of a gamete donor (eggs or sperm) and that of the intended parents. The goal of this pairing is to reduce the risk of passing on genetic diseases to the offspring.
This procedure involves comparing the DNA of the donor with that of the recipient or the recipient couple. To achieve this, a test is conducted using a blood analysis. Each member of the couple undergoes this analysis. Once the blood is drawn, potential genetic mutations associated with hereditary diseases are examined.
If the donor and the recipient are carriers of mutations in the same gene, this pairing will be ruled out to minimize the risk of the baby inheriting the disease.
Key factors in Genetic Matching
Various factors are analyzed in Genetic Matching. To determine the compatibility between the donor and the couple, everything from genetics itself to phenotypes or physical characteristics is studied.
Among the analyses that must be performed, histocompatibility also stands out. This factor is crucial to determine whether there is a risk of immune rejection or complications during pregnancy. Additionally, understanding the donor’s physical and mental health is essential to rule out any impact on the quality of the genetic material.
Purpose of Genetic Matching
The primary purpose of Genetic Matching is to ensure that the donor is the most suitable, both from a genetic and physical or phenotypic perspective. At Ovoclinic, Genetic Matching is a fundamental part of the treatment, carried out with the support of Ovobank, ensuring speed and quality by having access to a vast donor bank.
What happens if the couple is not compatible?
It is possible that the couple may not be genetically compatible with the chosen donor. This would be detected through Genetic Matching. Genetic Matching can analyze more than 100 genetic diseases, making it an increasingly utilized process that provides peace of mind to couples who wish to start a family.
